Keragaman Gen BG1 sebagai Kandidat Gen Penciri Ketahanan Penyakit pada Calon Galur Ayam IPB-D2
نویسندگان
چکیده
The BG1 gene is a disease resistance candidate in chicken, which located the MHC region. mechanism of known as an inhibitor T lymphocyte cell activation. This study aims to identify diversity SNP IPB-D2 chicken line. for new line from cross IPB-D1 was selected high body and good productivity. A total 27 DNA samples (G0) chickens 58 (G2) were sequenced genes. found 6 point mutations (g.4489 G>T, g.4712 C>T, g.4741 T>C, g.4747 g.4749 g.4761 G>A) deletion 2 nucleotide bases g.4758 - g.4759 delAT. combination SNPs forms 4 haplotypes. that changed amino acid composition g.4489 G>T cys> phen, C>T gln>codon stop, T>C val>ala G> gly> glu. All are classified polymorphic, low heterozygosity value, not Hardy-Weinberg equilibrium.
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ژورنال
عنوان ژورنال: Jurnal Ilmu Produksi dan Teknologi Hasil Peternakan
سال: 2022
ISSN: ['2303-2227', '2615-594X']
DOI: https://doi.org/10.29244/jipthp.10.3.144-151